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in february 2012, the fda approved janumet xr sitagliptin and metformin hci extended-release , a new treatment for type 2 diabetes that combines sitagliptin, which is the active component of januvia , with extended-release metformin in a once-daily formulation; cosopt pf dorzolamide hydrochloride-timolol maleate ophthalmic solution 2.

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