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chloramphenicol is effective against the three main bacterial causes of meningitis neisseria meningitidis, streptococcus pneumoniae, and haemophilus influenzae.

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chloramphenicol is a bacteriostatic agent that was used in the past for vre treatment, but it is not used often anymore due to lack of availability, clinical failures, development of resistance, and hematologic toxicity.

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use chloramphenicol with extreme caution in premature and full-term infants because they may be more sensitive to the effects of chloramphenicol, especially the risk of gray syndrome.

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