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digoxin absorption may also be affected by various concomitant therapy modulating gastric ph and p-glycoprotein see drug interactions 7 .
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daclatasvir major coadministration of daclatasvir with digoxin may increase digoxin exposure leading to increased or prolonged therapeutic effects and adverse events.
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has been noted that hydroxychloroquine could increase the plasma concentration of digoxin, thus to prevent the development of glycoside intoxication while receiving of these agents, it is necessary to decrease the dose of digoxin under control of plasma digoxin concentrations.
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