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Etodolac is more than 99 bound to plasma proteins, primarily to albumin, and is independent of etodolac concentration over the dose range studied.
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Frequency not reportedDry mouthulcerative stomatitiseructationpeptic ulcergastrointestinalGIbleedingperforationesophagitisesophageal stricturecardiospasmcolitisGI discomfortburning sensationgastralgiaupper abdominal discomfortglossitishematemesisrectal bleedingheartburnindigestionulcerative colitis exacerbatedCrohn’s disease exacerbated.
Since Lodine is extensively protein-boundit may be necessary to modify the dosage of other highly protein-bound drugs.
For people with high blood pressureThis medication may cause you to develop high blood pressureIf you already have high blood pressureit may worsen your condition or increase your chances of having a heart attack or stroke.
Only rate drugs or treatments you’ve triedIn your descriptionmention the branddoseand period of time that you used the drug or treatmentPlease share your positive and negative experiences with the drugand compare it with other treatments you have usedDo not include any personal information or links in your review.
If you have ever had an allergic reaction to any other NSAIDsuch as aspirinnaproxendiclofenacand indometacinor to any other medicineIf you have ever had a problem with bleeding from the stomach or intestinessuch as from a peptic or duodenal ulcerIf you have asthma or any other allergic disorderIf you have a heart conditionor a problem with your blood vessels or circulationIf you are pregnanttrying for a babyor breast-feedingIf you have ever had blood clotting problemsIf you have an inflammatory bowel disorder such as Crohn’s disease or ulcerative colitisIf you have high blood pressureIf you have a connective tissue disorder such as systemic lupus erythematosusThis is an inflammatory condition which is also called lupus or SLEIf you have any problems with the way your liver worksor if you have any problems with the way your kidneys workIf you are taking any other medicinesThis includes any medicines you are taking which are available to buy without a prescriptionas well as herbal and complementary medicines.
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no carcinogenic effect of gen-etodolac was observed in mice or rats receiving oral doses of 15 mg kg day 45 mg m 2 to 89 mg m 2 , respectively or less for periods of 2 years or 18 months, respectively.