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Patients twenty-three patients with chronic chf receiving furosemide, and 16 age-matched control patients without heart failure and not taking diuretics.
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Adverse effects of loop diuretics unrelated to the diuretic efficacy are rareand most adverse effects are due to abnormalities of fluid and electrolyte balanceHoweverloop diuretics can induce ototoxicity.
After oral administration furosemide is rapidly but incompletely absorbedresulting in an oral bioavailability of.
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medications include acetazolamide and furosemide.