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Concomitant administration of Lariammefloquineand other related compoundsegquininequinidine and chloroquinemay produce electrocardiographic abnormalities and increase the risk of convulsionssee WARNINGSIf these drugs are to be used in the initial treatment of severe malariaLariammefloquineadministration should be delayed at least 12 hours after the last doseThere is evidence that the use of halofantrine after mefloquine causes a significant lengthening of the QTc intervalClinically significant QTc prolongation has not been found with mefloquine alone.
Liver problemsnauseaupper stomach painitchingtired feelingloss of appetitedark urineclay-colored stoolsjaundiceyellowing of the skin or eyes
Mefloquine can pass into breast milk and may harm a nursing babyTell your doctor if you are breast-feeding a baby.
Periodic evaluation of hepatic function should be performed during prolonged prophylaxis.
You also should not use mefloquine to prevent malaria if you have a recent history of:
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because these experiences are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to lariam exposure.
