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The most common adverse reactions in the group treated with VYTORIN that led to treatment discontinuation and occurred at a rate greater than placebo were:
Ezetimibe and simvastatin can cause the breakdown of muscle tissuewhich can lead to kidney failureThis happens more often in womenin older adultsor in people who have kidney disease or poorly controlled hypothyroidismunderactive thyroid
VYTORIN is indicated for the reduction of elevated total-C and LDL-C in patients with homozygous familial hypercholesterolemiaas an adjunct to other lipid-lowering treatmentse.gLDL apheresisor if such treatments are unavailable.
It is very important to continue to follow your doctor’s advice about diet and exerciseIt may take up to 4 weeks before you get the full benefit of this drug.
Hypersensitivity reactionsincluding anaphylaxisangioedemarashand urticaria have been reported.
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