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Epristeridea novel 5 a-reductase inhibitoris an interesting drug in the treatment of BPHIt belongs to class of carboxy steroidIt has been shown to be an uncompetitive inhibitor against both testosterone and NADPHIts inhibitory action results from a preferential association to an enzyme binary complex containing NADP and henceincreases in testosterone concentration does not overcome its inhibitionIt is a specific inhibitor of type II 5 a-reductase isoenzymeIt also attenuates the growth rate of some androgen responsive prostate cancers34]
Salep OrchidOrchis masculathe salep orchid is known as salam mishri in AyurvedaIt is prescribed in case of prostate problems brought on by vata vitiation.
Noctoria is one of the bothersome LUTS and also most difficult to eliminate in aging menNocturnal polyurea associated with circadian change of arginine vasopressine and atrial natriuretic peptide in the elderly has been suggested as the most dominant type of nocturiaDesmopressin is effective in treating nocturia to improve the patients QOLalthough a few adverse events such as hypernatremia might occur45]
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