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Although metoclopramide may increase the bioavailability of levodopa by increasing gastric emptying.metoclopramide may also adversely affect disease control by its dopamine receptor antagonistic properties.

As with levodopa.treatment with SINEMET may increase the possibility of upper gastrointestinal hemorrhage in patients with a history of peptic ulcer.

The side effects associated with levodopa.including dizziness upon rising.confusion.movement disorders.nausea.and hallucinations.all can be increased by selegiline (Eldepryl).Sinemet is the brand name of the combination medicine that contains the drugs levodopa and carbidopa.

Tell your doctor about all prescription.non-prescription.illegal.recreational.herbal.nutritional.or dietary drugs you’re taking.especially.

Sinemet is indicated in the treatment of Parkinson’s disease.post-encephalitic parkinsonism.and symptomatic parkinsonism that may follow carbon monoxide intoxication or manganese intoxication.

Your doctor will probably gradually decrease your dose of Sinemet if you stop taking it.

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