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The effect of amantadine on embryofetal and peri-postnatal development has not been adequately tested, that is, in studies conducted under good laboratory practice glp and according to current recommended methodology. read more →
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Medications with significant anticholinergic activity, such as olanzapine, may potentiate the anticholinergic effects of amantadine, and may increase the risk of antimuscarinic-related side effects. read more →
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2018
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The study concluded that amantadine has an acceptable acute tolerability at single doses up to 150mg day, with the most common side effect being transient appetite decrease. read more →
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2018