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Trazodone inhibits the reuptake of serotonin, but possesses a far lower affinity for the serotonin transporter sert than the classical selective serotonin reuptake inhibitors ssris , such as fluoxetine prozac and citalopram celexa .

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in 1 of 3 placebo controlled, continuous dosing trials and 1 placebo controlled, intermittent dosing trial of fluoxetine in pmdd, treatment emergent adverse events reporting rates were assessed.

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62 65 norfluoxetine, a primary active metabolite of fluoxetine, produces a similar effect on allopregnanolone levels in the brains of mice.

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examples of such drugs are carbamazepine , phenytoin and phenobarbital for epilepsy , fluoxetine and paroxetine for depression , rifampicin antibiotic and verapamil for cardiac arrhythmias etc.


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