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the 2001 study noted 5 adolescents on paxil and one on placebo demonstrated suicidal ideation, or self-harm.
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adhesion of cancer cells, in particular colon cancer cells, is stimulated by exposure to increased extracellular pressure through a cytoskeleton-dependent signaling mechanism requiring fak, src, akt, and paxillin.
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as with many new drug applications, the fda convened a panel of non-governmental experts to determine paxil s fate.
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increased extracellular pressure appears to activate fak through a complex dual pathway requiring an intact cytoskeleton and paxillin as well as cytoskeleton-independent activation of src and pi3k.
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