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Do not crush or chew extended-release tablets. Doing so can release all of the drug at once.increasing the risk of side effects. Also.do not split the tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing.
Because children commonly have gastrointestinal illnesses that lead to vomiting.they may be particularly susceptible to hypertensive episodes resulting from abrupt inability to take medication.
Combining alcohol with clonidine may cause a dangerous sedative effect. It may slow your reflexes.cause poor judgment.and cause sleepiness.
Based on observations in patients in a state of alcoholic delirium it has been suggested that high intravenous doses of clonidine may increase the arrhythmogenic potential (QTprolongation.ventricular fibrillation) of high intravenous doses of haloperidol. Causal relationship and relevance for clonidine oral tablets have not been established.
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